Numerous studies have shown evidence supporting the benefits of universal newborn screening for primary immunodeficiencies (PID) and for Spinal Muscular Atrophy (SMA).We have developed a four-plex, real-time PCR assay to screen for Severe Combined Immune Deficiencies (SCID), X-linked agammaglobulinemia (XLA), and SMA in DNA extracted from a single
Deep neural networks have been successfully applied in learning the board games Go, chess, and shogi without prior knowledge by making use of reinforcement learning.Although starting from zero knowledge has been shown to yield impressive results, it is associated with high computationally costs especially for complex games.With this paper, we prese
Despite the essential role of mayflies (Ephemeroptera) in freshwater ecosystems and their long-term use in research and routine biomonitoring in the Carpathian and Pannonian ecoregions, their distribution data are fragmentary and outdated.All published and unpublished data on mayflies from Slovakia was gathered and a database of > 15,000 spe
The article studies the representation of Spanish Kings in the mid-16th century, in sculpture and painting.The image of the monarch in that time has a specific character related to the antique allusions.This analysis demonstrates some specific Unclassified features of the Spanish Renaissance culture with its pragmatic attitude to the antique tradit